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PHARMACEUTICAL FORMULATIONS AND METHODS COMPRISING

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专利名称:PHARMACEUTICAL FORMULATIONS AND

METHODS COMPRISING INTRANASALMORPHINE

发明人:ACHARI, Raja G.,BEHL, Charanjit

R.,DEMEIRELES, Jorge C.,DUA,

Ramneik,ROMEO, Vincent,,SILENO, Anthony,P.

申请号:EP00936212.0申请日:20000523公开号:EP1183027A1公开日:20020306

摘要:The present invention relates to a pharmaceutical formulation for intranasaladministration comprising morphine or pharmaceutically acceptable salt thereof at a pHfrom about 3.0 to about 7.0. Such formulations provide enhanced absorption of morphineor pharmaceutically acceptable salts thereof. In one embodiment, the present inventionprovides a method for eliciting an analgesic or anaesthetic response in a mammal whichincludes nasally administering a therapeutically effective amount of morphine orpharmaceutically acceptable salt thereof at a pH from about 3.0 to about 7.0.

申请人:NASTECH PHARMACEUTICAL CO.

地址:45 Davids Drive Hauppauge, NY 11788 US

国籍:US

代理机构:Gowshall, Jonathan Vallance

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