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Miglitol_72432-03-2_DataSheet_MedChemExpress

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Product Data SheetProduct Name:CAS No.: Cat.No.:Cat. No.:MWt:Formula:Purity :Miglitol72432-03-2HY-B0481HYB0481207.22C8H17NO5>98%Solubility:DMSO3mg/mL;Water<1DMSO 3 mg/mL; Water 1 mg/mLmg/mLMechanisms: Pathways:Others; Target:Others Biological Activity:Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdownMilitliltidibtidthttbihibitithbilitfthtittbkdcomplex carbohydrates into glucose. Target: Others Miglitol is an oral anti-diabetic drug that acts by inhibiting the ability of the patient to breakdowncomplex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishinggreater glycemic control by preventing the digestion of carbohydrates (such as disaccharides,oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body.Miglitol inhibits glycoside hydrolase enzymes called alpha-glucosidases. Since miglitol works bypreventingdigestionofcarbohydratesitlowersthedegreeofpostprandialhyperglycemiaItmustbepreventing digestion of carbohydrates, it lowers the degree of postprandial hyperglycemia. It must betaken at the start of main meals to have maximal effect. Its effect will depend on the amount of non-monosaccharide carbohydrates in a...References:[1]. Fukaya, N., et al., The alpha-glucosidase inhibitor miglitol delays the development of diabetesand dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats. Eur J Pharmacol, 2009.624(1-3): p. 51-7. [2]. Hirata, A., et al., Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes inballoon-injured diabetic rats. Horm Metab Res, 2009. 41(3): p. 213-20. Caution: Not fully tested. For research purposes onlyMedchemexpress LLCwww.medchemexpress.com18Wilkinson Way, Princeton, NJ 08540,USAess.com Web: www.medchemexpress.comEmail: info@medchemexpr

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